Translational Metabolomics Shared Resource

Overview of Services

The Translational Metabolomics (Redox & Bioenergetics, Imaging, Mass Spectrometry) Shared Resource (TraMSR) provides expertise and state-of-the-art instrumentation for cancer center members to explore cancer metabolism by enabling users to run mass spectrometry analyses of tumor metabolome, bioenergetic and redox function analyses, and pre-clinical imaging.

Services

Mass Spec

• Sample Preparation
• Metabolomics
• Lipidomics
• Glycomics
• Glycoproteomics
• Mass Spec Imaging
• Data analysis

Redox and Bioenergetics

• ROS measurements and probes
• GSH/GSSG measurements
• Redox immunoblotting
• Metabolic pathway profiling
• Mitochondrial oxygen consumption
• Glycolytic function
• Mitochondrial membrane potential
• Metabolic reprogramming

Small Animal Imaging

• Bioluminescence and florescence imaging in pre-clinical rodent models
• CT imaging
• NIR and Short-Wave Infrared Imaging (SWIR)

Leadership

Karin Hoffmeister, MD

Director, Translational Metabolomics

Mass Spectometry

Kazuhiro Aoki
Associate Professor, Cell Biology, Neurobiology and Anatomy
kaoki@mcw.edu

Redox & Bioenergetics

Jacek Zielonka, PhD
Assistant Professor; Director, Redox & Bioenergetics Shared Resource
jzielonk@mcw.edu

Pre-Clinical Imaging

Amit Joshi, PhD
Associate Professor, Biomedical Engineering
ajoshi@mcw.edu

Location and hours of operation

Center for Cancer Discovery, MS and Redox Bioenergetics N1130, Pre-Clinical Imaging LL N0960
M-F from 8 a.m.-5 p.m.

Scheduling

For support, please submit a TraMSR iLab request.

Contacts