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About

Translational Metabolomics Shared Resource

Overview of Services

The Translational Metabolomics (Redox & Bioenergetics, Imaging, Mass Spectrometry) Shared Resource (TraMSR) provides expertise and state-of-the-art instrumentation for cancer center members to explore cancer metabolism by enabling users to run mass spectrometry analyses of tumor metabolome, bioenergetic and redox function analyses, and pre-clinical imaging.

Services


Mass Spec

  • Sample Preparation
  • Metabolomics
  • Lipidomics
  • Glycomics
  • Glycoproteomics
  • Mass Spec Imaging
  • Data analysis

Redox and Bioenergetics

  • ROS measurements and probes
  • GSH/GSSG measurements
  • Redox immunoblotting
  • Metabolic pathway profiling
  • Mitochondrial oxygen consumption
  • Glycolytic function
  • Mitochondrial membrane potential
  • Metabolic reprogramming

Small Animal Imaging

  • Bioluminescence and florescence imaging in pre-clinical rodent models
  • CT imaging
  • NIR and Short-Wave Infrared Imaging (SWIR)

Leadership

Karin Hoffmeister, MD

Director, Translational Metabolomics

 


Mass Spectometry

Kazuhiro Aoki
Associate Professor, Cell Biology, Neurobiology and Anatomy
kaoki@mcw.edu

Redox & Bioenergetics

Jacek Zielonka, PhD
Assistant Professor; Director, Redox & Bioenergetics Shared Resource
jzielonk@mcw.edu

Pre-Clinical Imaging

Amit Joshi, PhD
Associate Professor, Biomedical Engineering
ajoshi@mcw.edu

Location and hours of operation

Center for Cancer Discovery, MS and Redox Bioenergetics N1130, Pre-Clinical Imaging LL N0960
M-F from 8 a.m.-5 p.m.

Scheduling

For support, please submit a TraMSR iLab request.

 

Contacts

Name Role Phone Email Location
Kazuhiro Aoki
Mass Spec, Director
 

 
TraM_MassSpec@mcw.edu
 
N1150
 
Jacek Zielonka
Redox, Director
 

 
jzielonk@mcw.edu
 
N1150
 
Amit Joshi
Preclinical Imaging, Director
 

 
ajoshi@mcw.edu
 
N0960