Translational Metabolomics Shared Resource

Overview of Services

The Translational Metabolomics (Redox & Bioenergetics, Imaging, Mass Spectrometry) Shared Resource (TraMSR) provides expertise and state-of-the-art instrumentation for cancer center members to explore cancer metabolism by enabling users to run mass spectrometry analyses of tumor metabolome, bioenergetic and redox function analyses, and pre-clinical imaging.

Services


Mass Spec

  • Sample Preparation
  • Metabolomics
  • Lipidomics
  • Glycomics
  • Glycoproteomics
  • Mass Spec Imaging
  • Data analysis

Redox and Bioenergetics

  • ROS measurements and probes
  • GSH/GSSG measurements
  • Redox immunoblotting
  • Metabolic pathway profiling
  • Mitochondrial oxygen consumption
  • Glycolytic function
  • Mitochondrial membrane potential
  • Metabolic reprogramming

Small Animal Imaging

  • Bioluminescence and florescence imaging in pre-clinical rodent models
  • CT imaging
  • NIR and Short-Wave Infrared Imaging (SWIR)

Leadership

Peter S. LaViolette, PhD, MS
Robert C. Olson Professor of Radiology
Director, Translational Metabolomics Shared Resource
Medical College of Wisconsin
plaviole@mcw.edu


Mass Spectometry

Kazuhiro Aoki
Associate Professor, Cell Biology, Neurobiology and Anatomy
kaoki@mcw.edu

Redox & Bioenergetics

Jacek Zielonka, PhD
Assistant Professor; Director, Redox & Bioenergetics Shared Resource
jzielonk@mcw.edu

Pre-Clinical Imaging

Amit Joshi, PhD
Associate Professor, Biomedical Engineering
ajoshi@mcw.edu

Location and hours of operation

Translational and Biomedical Research Center (TBRC)
M-F from 8 a.m.-5 p.m.

Scheduling

For support, please submit a TraMSR iLab request.

 

Contacts

Name Role Phone Email Location
Peter LaViolette
Core Administrator
 

 
plaviole@mcw.edu