ALERT

The iLab Core Management System functionality should only be minimally impacted by the transition to Workday when system changes are implemented on January 10th.   Service requests, reservations, and forms will remain the same and requested services can be performed by the core facilities as usual except for the Saturday January 10th outage. Please reach out to ilab@mcw.edu with questions or concerns.

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About

Translational Metabolomics Shared Resource

Overview of Services

The Translational Metabolomics (Redox & Bioenergetics, Imaging, Mass Spectrometry) Shared Resource (TraMSR) provides expertise and state-of-the-art instrumentation for cancer center members to explore cancer metabolism by enabling users to run mass spectrometry analyses of tumor metabolome, bioenergetic and redox function analyses, and pre-clinical imaging.

Services


Mass Spec

  • Sample Preparation
  • Metabolomics
  • Lipidomics
  • Glycomics
  • Glycoproteomics
  • Mass Spec Imaging
  • Data analysis

Redox and Bioenergetics

  • ROS measurements and probes
  • GSH/GSSG measurements
  • Redox immunoblotting
  • Metabolic pathway profiling
  • Mitochondrial oxygen consumption
  • Glycolytic function
  • Mitochondrial membrane potential
  • Metabolic reprogramming

Small Animal Imaging

  • Bioluminescence and florescence imaging in pre-clinical rodent models
  • CT imaging
  • NIR and Short-Wave Infrared Imaging (SWIR)

Leadership

Karin Hoffmeister, MD

Director, Translational Metabolomics

 


Mass Spectometry

Kazuhiro Aoki
Associate Professor, Cell Biology, Neurobiology and Anatomy
kaoki@mcw.edu

Redox & Bioenergetics

Jacek Zielonka, PhD
Assistant Professor; Director, Redox & Bioenergetics Shared Resource
jzielonk@mcw.edu

Pre-Clinical Imaging

Amit Joshi, PhD
Associate Professor, Biomedical Engineering
ajoshi@mcw.edu

Location and hours of operation

Center for Cancer Discovery, MS and Redox Bioenergetics N1130, Pre-Clinical Imaging LL N0960
M-F from 8 a.m.-5 p.m.

Scheduling

For support, please submit a TraMSR iLab request.

 

Contacts

Name Role Phone Email Location
Kazuhiro Aoki
Mass Spec, Director
 

 
TraM_MassSpec@mcw.edu
 
N1150
 
Jacek Zielonka
Redox, Director
 

 
jzielonk@mcw.edu
 
N1150
 
Amit Joshi
Preclinical Imaging, Director
 

 
ajoshi@mcw.edu
 
N0960