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(hide this warning on this page)(Formerly Mouse Transgenic Core)
The RMR provides access to the following services for rodent models
Assists research staff with procedures involving production and maintenance of transgenic mouse and rat strains. The Core provides both sperm and embryo cryopreservation/recovery, IVF, ICSI, pronuclear microinjection of CRISPR and DNA/BAC constructs. We are also available for consultation involving colony breeding issues.
The laboratory is located in the vivarium of the Translational and Biomedical Research Center at MCW and is equipped to perform all procedures involving production and maintenance of transgenic or knock-out mice. Instrumentation includes 2 injection workstations (Nikon inverted phase contrast microscope with Hoffman modulation optics, temperature-controlled injection stage, air-suspended injection table, Eppendorf motor-driven injection system), microforge, needle puller, Nikon stereo zoom microscope, surgical microscopes and dewars for storage of cryopreserved mouse germplasm.
Aron Geurts, PhD
Professor, Department of Physiology
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Jason Klotz |
414-456-7580
|
jklotz@mcw.edu
|
BSB
|
|
| Michael Grzybowski |
Geurts Lab manager
|
414-955-7576
|
mgrzybowski@mcw.edu
|
BSB
|
| Service list |
| ► Mouse Service Lines (1) | |||
| Name | Description | Price | |
|---|---|---|---|
| NRG/Jax mice |
the RMR holds a small breeding colony of these mice for INTERNAL investigators and non-profit research use ONLY under the terms below. Offspring are available on as available basis. contact transgeniccore@mcw.edu for more informaiton.
An academic institution may use the stock#007799, NOD.Cg-Rag1<tm1Mom> Il2rg<tm1Wjl>/SzJ, and stock#005557, NOD.Cg-Rag1tm1Mom Il2rgtm1Wjl/SzJ for academic research, usually under grant funding. Mice may not be transferred or used for commercial use. The mouse or progeny of any kind, or a modified version of the mouse may not be shipped to any party (e.g. a different institution, researcher or company etc.), outside of the institution without the prior written consent of Jackson. Any researcher using a Jackson mouse should be aware of the full and correct ID of the mouse model and that there may be specific restrictions on use of any strain. |
Inquire | |
| ► Strain Maintenance (1) | |||
| Name | Description | Price | |
| Strain maintenance (mice, cage days) |
includes BRC per diem cost |
Inquire | |