Overview of Services
The Oxford Instruments Center for Advanced Microscopy - Electron Microscopy Core at the Medical College of Wisconsin is an institutionally available research service unit managed on behalf of the Medical College by the Department of Cell Biology, Neurobiology and Anatomy. OxCAM-EM encompasses both Light and Electron Microscopy services and is located on the 4th floor of the Macc Fund building. OxCAM-EM is open to all Medical College of Wisconsin faculty, staff, and students; investigators at affiliated institutions and other non-MCW investigators.
EM Services include:
The Electron Microscopy Facility provides service, consultation for research and some training for projects requiring transmission electron microscopy. The Facility operates on a fee-for-service basis.
- Complete tissue processing facilities
- Immunoelectron microscopy
- Negative staining
- Enzyme cytochemistry
- Ultrastructural Electron Tomography
OxCAM Light Microscopy Services include:
OxCAM relies primarily on a teach and train model offering the following for the microscopes located within the core.
- Consultations
- Microscope demo sessions
- Full training sessions to become independent users
- Guided use sessions
OxCAM Light Microscopy Imaging Systems:
Benchtop Spinning Disk Confocals:
- Andor BC43
- Andor BC43 with live cell chamber
Advanced Microscopes:
- Andor Dragonfly 502 spinning disk with Mosaic system for photostimulation
- Andor Dragonfly 620 SR spinning disk microscope with STORM / TIRF capabilities
- Nikon N-SIM structured illumination microscope
- Abberior Facility Line STED microscope
Image Analysis:
- Imaris for Cores 3D Image Analysis
Leadership
Ashish Gadicherla | OxCAM-EM Director
Rob Goodwin | EM Core Manager
Megan Harwig | OxCAM Light Microscopy Manager
Location and hours of operation
| Hours |
Location |
|
Monday-Friday
6:30am - 6:00pm
|
MACC Fund Building 4041
|
For general enquiries please use the following email address: HRICmicroscopy@mcw.edu
Other imaging cores on campus:
CRI imaging core
- Zeiss Confocal Microscope
- Zeiss Confocal / Multiphoton Microscope
- Zeiss Upright Microscope
- Zeiss Inverted Microscope
- PALM Laser Microdissection
- Laser Scanning Cytometry
- Hamamatsu (Brightfield) slide scanning drop off service
- VS120 (Fluorescence) slide scanning drop off service
- Image Analysis Consultation service
CVRC Confocal Core
- Nikon A1R Laser Scanning Inverted Confocal
- Nikon C2+ Laser Scanning Inverted Confocal
- Nikon E-55i upright widefield / brightfield microscope
- Nikon TE-2000 inverted widefield / brightfield / phase microscope
- Keyence BZ-X810
- Evident Scientific VS-200 slide scanner with SILA module coming soon (Fall 2025)
NRC Microscopy Core
- Imaris Image Processing Computer
- Leica SP8 Upright Confocal Microscope
- Stereoscope
- Tissue clearing service
- Lightsheet Microscopy service
- Nikon Multiphoton (not available yet as shared resource)
Structural Biology Shared Resources (SBSR)
Versiti
- Nikon Ti2 Widefield inverted microscope
- Nikon CSU-W1 Spinning Disk inverted confocal + SoRa
- 3i upright spinning disk confocal
- Olympus Laser Scanning Confocal and Multi-photon
- EVOS M7000
- Motic EasyScan Pro6 Digital Slide Scanner
- Zeiss Lumar Stereo Microscope
- Analysis stations
- Nikon NIS-Elements
- Slidebook
- Imaris - East
- Imaris - West
- Nikon AxR (not available yet as shared resource)
- Nikon Multiphoton (not available yet as shared resource)
Helpful Links
The CoreMarketplace: MCW-Oxford Instruments Center for Advanced Microscopy- Electron Microscopy Core
How to cite the OxCAM-EM Core:
The Oxford Instruments Center for Advanced Microscopy - Electron Microscopy Core (RRID:SCR_026315) at the Medical College of Wisconsin is an institutionally available research service unit managed on behalf of the Medical College by the Department of Cell Biology, Neurobiology and Anatomy.
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