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 * * * Happy Holidays from the iLab Support Team * * *

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ALERT

The iLab Core Management System functionality should only be minimally impacted by the transition to Workday when system changes are implemented on January 10th.   Service requests, reservations, and forms will remain the same and requested services can be performed by the core facilities as usual except for the Saturday January 10th outage. Please reach out to ilab@mcw.edu with questions or concerns.

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About

Oxford Instruments Center for Advanced Microscopy - Electron Microscopy Core

Overview of Services                                                                                                                                                         

The Oxford Instruments Center for Advanced Microscopy - Electron Microscopy Core at the Medical College of Wisconsin is an institutionally available research service unit managed on behalf of the Medical College by the Department of Cell Biology, Neurobiology and Anatomy. OxCAM-EM encompasses both Light and Electron Microscopy services and is located on the 4th floor of the Macc Fund building. OxCAM-EM is open to all Medical College of Wisconsin faculty, staff, and students; investigators at affiliated institutions and other non-MCW investigators.
 

EM Services include:

The Electron Microscopy Facility provides service, consultation for research and some training for projects requiring transmission electron microscopy. The Facility operates on a fee-for-service basis.
  • Complete tissue processing facilities
  • Immunoelectron microscopy
  • Negative staining
  • Enzyme cytochemistry
  • Ultrastructural Electron Tomography
 

OxCAM Light Microscopy Services include:

OxCAM relies primarily on a teach and train model offering the following for the microscopes located within the core.
  • Consultations
  • Microscope demo sessions
  • Full training sessions to become independent users
  • Guided use sessions
 

OxCAM Light Microscopy Imaging Systems: 

Benchtop Spinning Disk Confocals:
  • Andor BC43
  • Andor BC43 with live cell chamber
Advanced Microscopes:
  • Andor Dragonfly 502 spinning disk with Mosaic system for photostimulation
  • Andor Dragonfly 620 SR spinning disk microscope with STORM / TIRF capabilities
  • Nikon N-SIM structured illumination microscope
  • Abberior Facility Line STED microscope

Image Analysis: 

  • Imaris for Cores 3D Image Analysis 

 

Leadership

Ashish Gadicherla | OxCAM-EM Director

Rob Goodwin | EM Core Manager

Megan Harwig | OxCAM Light Microscopy Manager

Location and hours of operation

Hours Location

Monday-Friday

6:30am - 6:00pm          

MACC Fund Building 4041

 

 

For general enquiries please use the following email address: HRICmicroscopy@mcw.edu

 

Other imaging cores on campus: 

CRI imaging core 

  • Zeiss Confocal Microscope
  • Zeiss Confocal / Multiphoton Microscope
  • Zeiss Upright Microscope
  • Zeiss Inverted Microscope
  • PALM Laser Microdissection
  • Laser Scanning Cytometry
  • Hamamatsu (Brightfield) slide scanning drop off service
  • VS120 (Fluorescence) slide scanning drop off service 
  • Image Analysis Consultation service

CVRC Confocal Core

  • Nikon A1R Laser Scanning Inverted Confocal
  • Nikon C2+ Laser Scanning Inverted Confocal
  • Nikon E-55i upright widefield / brightfield microscope
  • Nikon TE-2000 inverted widefield / brightfield / phase microscope
  • Keyence BZ-X810 
  • Evident Scientific VS-200 slide scanner with SILA module coming soon (Fall 2025)

NRC Microscopy Core

  • Imaris Image Processing Computer
  • Leica SP8 Upright Confocal Microscope
  • Stereoscope
  • Tissue clearing service
  • Lightsheet Microscopy service
  • Nikon Multiphoton (not available yet as shared resource)

Structural Biology Shared Resources (SBSR)

  • Thermo Glacios 200 kV cryo-TEM for single particle analysis

Versiti

  • Nikon Ti2 Widefield inverted microscope
  • Nikon CSU-W1 Spinning Disk inverted confocal + SoRa
  • 3i upright spinning disk confocal
  • Olympus Laser Scanning Confocal and Multi-photon
  • EVOS M7000
  • Motic EasyScan Pro6 Digital Slide Scanner
  • Zeiss Lumar Stereo Microscope
  • Analysis stations
    • Nikon NIS-Elements
    • Slidebook
    • Imaris - East
    • Imaris - West
  • Nikon AxR (not available yet as shared resource)
  • Nikon Multiphoton (not available yet as shared resource)

 

Helpful Links

 The CoreMarketplace: MCW-Oxford Instruments Center for Advanced Microscopy- Electron Microscopy Core 

 

How to cite the OxCAM-EM Core: 

The Oxford Instruments Center for Advanced Microscopy - Electron Microscopy Core (RRID:SCR_026315) at the Medical College of Wisconsin is an institutionally available research service unit managed on behalf of the Medical College by the Department of Cell Biology, Neurobiology and Anatomy. 

 

Contacts

Name Role Phone Email Location
Ashish Gadicherla
Core Director
 
414 955 8662
 
agadicherla@mcw.edu
 
MACC Fund 4054
 
Rob Goodwin
Electron Microscopy Core Manager
 
414 955 8344
 
rgoodwin@mcw.edu
 
MACC Fund 4038
 
Megan Harwig
Light Microscopy Core Manager
 
414 955 8520
 
mcharwig@mcw.edu
 
MACC Fund 4037